Ghatail upazila on the north, Mirzapur upazila on the south, Bhaluka, Sreepur (Gazipur) and Kaliakair upazilas on the east, Kalihati and Basail upazilas on the west.

Sakhipur thana was established in 1976 and was turned into an upazila in 1983. The upazila consists of six union parishads, 65 mouzas and 123 villages.

Sakhipur Upazila is located in Tangail District. Upazilla(s)/Thana(s) in Tangail are Basail Upazila, Bhuapur Upazila, Delduar Upazila, Ghatail Upazila, Gopalpur Upazila, Kalihati Upazila, Madhupur Upazila, Mirzapur Upazila, Nagarpur Upazila, Sakhipur Upazila, Tangail Sadar Upazila.